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- Title
Gene expression analyses of immune responses in Atlantic salmon during early stages of infection by salmon louse (Lepeophtheirus salmonis) revealed bi-phasic responses coinciding with the copepod-chalimus transition.
- Authors
Tadiso, Tariku Markos; Krasnov, Aleksei; Skugor, Stanko; Afanasyev, Sergey; Hordvik, Ivar; Nilsen, Frank
- Abstract
The salmon louse (Lepeophtheirus salmonis Krøyer), an ectoparasitic copepod with a complex life cycle causes significant losses in salmon aquaculture. Pesticide treatments against the parasite raise environmental concerns and their efficacy is gradually decreasing. Improvement of fish resistance to lice, through biological control methods, needs better understanding of the protective mechanisms. We used a 21 k oligonucleotide microarray and RT-qPCR to examine the time-course of immune gene expression changes in salmon skin, spleen, and head kidney during the first 15 days after challenge, which encompassed the copepod and chalimus stages of lice development.
- Publication
BMC genomics, 2011, Vol 12, p141
- ISSN
1471-2164
- Publication type
Journal Article
- DOI
10.1186/1471-2164-12-141