We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Role of an ER stress response element in regulating the bidirectional promoter of the mouse CRELD2 - ALG12 gene pair.
- Authors
Oh-Hashi, Kentaro; Koga, Hisashi; Ikeda, Shun; Shimada, Kiyo; Hirata, Yoko; Kiuchi, Kazutoshi
- Abstract
Recently, we identified cysteine-rich with EGF-like domains 2 (CRELD2) as a novel endoplasmic reticulum (ER) stress-inducible gene and characterized its transcriptional regulation by ATF6 under ER stress conditions. Interestingly, the CRELD2 and asparagine-linked glycosylation 12 homolog (ALG12) genes are arranged as a bidirectional (head-to-head) gene pair and are separated by less than 400 bp. In this study, we characterized the transcriptional regulation of the mouse CRELD2 and ALG12 genes that is mediated by a common bidirectional promoter.
- Publication
BMC genomics, 2010, Vol 11, p664
- ISSN
1471-2164
- Publication type
Journal Article
- DOI
10.1186/1471-2164-11-664