We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Expression, tandem repeat copy number variation and stability of four macrosatellite arrays in the human genome.
- Authors
Tremblay, Deanna C; Alexander, Graham, Jr; Moseley, Shawn; Chadwick, Brian P
- Abstract
Macrosatellites are some of the largest variable number tandem repeats in the human genome, but what role these unusual sequences perform is unknown. Their importance to human health is clearly demonstrated by the 4q35 macrosatellite D4Z4 that is associated with the onset of the muscle degenerative disease facioscapulohumeral muscular dystrophy. Nevertheless, many other macrosatellite arrays in the human genome remain poorly characterized.
- Publication
BMC genomics, 2010, Vol 11, p632
- ISSN
1471-2164
- Publication type
Journal Article
- DOI
10.1186/1471-2164-11-632