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- Title
SHV Lactamase Engineering Database: a reconciliation tool for SHV β-lactamases in public databases.
- Authors
Thai, Quan K; Pleiss, Juergen
- Abstract
SHV β-lactamases confer resistance to a broad range of antibiotics by accumulating mutations. The number of SHV variants is steadily increasing. 117 SHV variants have been assigned in the SHV mutation table (http://www.lahey.org/Studies/). Besides, information about SHV β-lactamases can be found in the rapidly growing NCBI protein database. The SHV β-Lactamase Engineering Database (SHVED) has been developed to collect the SHV β-lactamase sequences from the NCBI protein database and the SHV mutation table. It serves as a tool for the detection and reconciliation of inconsistencies, and for the identification of new SHV variants and amino acid substitutions.
- Publication
BMC genomics, 2010, Vol 11, p563
- ISSN
1471-2164
- Publication type
Journal Article
- DOI
10.1186/1471-2164-11-563