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- Title
Proteome-wide survey of phosphorylation patterns affected by nuclear DNA polymorphisms in Arabidopsis thaliana.
- Authors
Riaño-Pachón, Diego Mauricio; Kleessen, Sabrina; Neigenfind, Jost; Durek, Pawel; Weber, Elke; Engelsberger, Wolfgang R; Walther, Dirk; Selbig, Joachim; Schulze, Waltraud X; Kersten, Birgit
- Abstract
Protein phosphorylation is an important post-translational modification influencing many aspects of dynamic cellular behavior. Site-specific phosphorylation of amino acid residues serine, threonine, and tyrosine can have profound effects on protein structure, activity, stability, and interaction with other biomolecules. Phosphorylation sites can be affected in diverse ways in members of any species, one such way is through single nucleotide polymorphisms (SNPs). The availability of large numbers of experimentally identified phosphorylation sites, and of natural variation datasets in Arabidopsis thaliana prompted us to analyze the effect of non-synonymous SNPs (nsSNPs) onto phosphorylation sites.
- Publication
BMC genomics, 2010, Vol 11, p411
- ISSN
1471-2164
- Publication type
Journal Article
- DOI
10.1186/1471-2164-11-411