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- Title
Evolutionary conservation of essential and highly expressed genes in Pseudomonas aeruginosa.
- Authors
Dötsch, Andreas; Klawonn, Frank; Jarek, Michael; Scharfe, Maren; Blöcker, Helmut; Häussler, Susanne
- Abstract
The constant increase in development and spread of bacterial resistance to antibiotics poses a serious threat to human health. New sequencing technologies are now on the horizon that will yield massive increases in our capacity for DNA sequencing and will revolutionize the drug discovery process. Since essential genes are promising novel antibiotic targets, the prediction of gene essentiality based on genomic information has become a major focus.
- Publication
BMC genomics, 2010, Vol 11, p234
- ISSN
1471-2164
- Publication type
Journal Article
- DOI
10.1186/1471-2164-11-234