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Title
Phylogenetic analysis of fungal ABC transporters.
Authors
Kovalchuk, Andriy; Driessen, Arnold J M
Abstract
The superfamily of ABC proteins is among the largest known in nature. Its members are mainly, but not exclusively, involved in the transport of a broad range of substrates across biological membranes. Many contribute to multidrug resistance in microbial pathogens and cancer cells. The diversity of ABC proteins in fungi is comparable with those in multicellular animals, but so far fungal ABC proteins have barely been studied.