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- Title
Comparative genomics and proteomics of Helicobacter mustelae, an ulcerogenic and carcinogenic gastric pathogen.
- Authors
O'Toole, Paul W; Snelling, William J; Canchaya, Carlos; Forde, Brian M; Hardie, Kim R; Josenhans, Christine; Graham, Robert Lj; McMullan, Geoff; Parkhill, Julian; Belda, Eugenio; Bentley, Stephen D
- Abstract
Helicobacter mustelae causes gastritis, ulcers and gastric cancer in ferrets and other mustelids. H. mustelae remains the only helicobacter other than H. pylori that causes gastric ulceration and cancer in its natural host. To improve understanding of H. mustelae pathogenesis, and the ulcerogenic and carcinogenic potential of helicobacters in general, we sequenced the H. mustelae genome, and identified 425 expressed proteins in the envelope and cytosolic proteome.
- Publication
BMC genomics, 2010, Vol 11, p164
- ISSN
1471-2164
- Publication type
Journal Article
- DOI
10.1186/1471-2164-11-164