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- Title
Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus.
- Authors
Skalsky, Rebecca L; Vanlandingham, Dana L; Scholle, Frank; Higgs, Stephen; Cullen, Bryan R
- Abstract
MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally regulate gene expression in a variety of organisms, including insects, vertebrates, and plants. miRNAs play important roles in cell development and differentiation as well as in the cellular response to stress and infection. To date, there are limited reports of miRNA identification in mosquitoes, insects that act as essential vectors for the transmission of many human pathogens, including flaviviruses. West Nile virus (WNV) and dengue virus, members of the Flaviviridae family, are primarily transmitted by Aedes and Culex mosquitoes. Using high-throughput deep sequencing, we examined the miRNA repertoire in Ae. albopictus cells and Cx. quinquefasciatus mosquitoes.
- Publication
BMC genomics, 2010, Vol 11, p119
- ISSN
1471-2164
- Publication type
Journal Article
- DOI
10.1186/1471-2164-11-119