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- Title
ArachnoServer: a database of protein toxins from spiders.
- Authors
Wood, David L A; Miljenović, Tomas; Cai, Shuzhi; Raven, Robert J; Kaas, Quentin; Escoubas, Pierre; Herzig, Volker; Wilson, David; King, Glenn F
- Abstract
Venomous animals incapacitate their prey using complex venoms that can contain hundreds of unique protein toxins. The realisation that many of these toxins may have pharmaceutical and insecticidal potential due to their remarkable potency and selectivity against target receptors has led to an explosion in the number of new toxins being discovered and characterised. From an evolutionary perspective, spiders are the most successful venomous animals and they maintain by far the largest pool of toxic peptides. However, at present, there are no databases dedicated to spider toxins and hence it is difficult to realise their full potential as drugs, insecticides, and pharmacological probes.
- Publication
BMC genomics, 2009, Vol 10, p375
- ISSN
1471-2164
- Publication type
Journal Article
- DOI
10.1186/1471-2164-10-375