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- Title
Gene organization and sequence analyses of transfer RNA genes in Trypanosomatid parasites.
- Authors
Padilla-Mejía, Norma E; Florencio-Martínez, Luis E; Figueroa-Angulo, Elisa E; Manning-Cela, Rebeca G; Hernández-Rivas, Rosaura; Myler, Peter J; Martínez-Calvillo, Santiago
- Abstract
The protozoan pathogens Leishmania major, Trypanosoma brucei and Trypanosoma cruzi (the Tritryps) are parasites that produce devastating human diseases. These organisms show very unusual mechanisms of gene expression, such as polycistronic transcription. We are interested in the study of tRNA genes, which are transcribed by RNA polymerase III (Pol III). To analyze the sequences and genomic organization of tRNA genes and other Pol III-transcribed genes, we have performed an in silico analysis of the Tritryps genome sequences.
- Publication
BMC genomics, 2009, Vol 10, p232
- ISSN
1471-2164
- Publication type
Journal Article
- DOI
10.1186/1471-2164-10-232