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- Title
Analysis of the Rickettsia africae genome reveals that virulence acquisition in Rickettsia species may be explained by genome reduction.
- Authors
Fournier, Pierre-Edouard; El Karkouri, Khalid; Leroy, Quentin; Robert, Catherine; Giumelli, Bernadette; Renesto, Patricia; Socolovschi, Cristina; Parola, Philippe; Audic, Stéphane; Raoult, Didier
- Abstract
The Rickettsia genus includes 25 validated species, 17 of which are proven human pathogens. Among these, the pathogenicity varies greatly, from the highly virulent R. prowazekii, which causes epidemic typhus and kills its arthropod host, to the mild pathogen R. africae, the agent of African tick-bite fever, which does not affect the fitness of its tick vector.
- Publication
BMC genomics, 2009, Vol 10, p166
- ISSN
1471-2164
- Publication type
Journal Article
- DOI
10.1186/1471-2164-10-166