Your institution may have access to this item. Find your institution then sign in to continue.
Title
Evolution of alternative and constitutive regions of mammalian 5'UTRs.
Authors
Resch, Alissa M; Ogurtsov, Aleksey Y; Rogozin, Igor B; Shabalina, Svetlana A; Koonin, Eugene V
Abstract
Alternative splicing (AS) in protein-coding sequences has emerged as an important mechanism of regulation and diversification of animal gene function. By contrast, the extent and roles of alternative events including AS and alternative transcription initiation (ATI) within the 5'-untranslated regions (5'UTRs) of mammalian genes are not well characterized.