We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
PlnTFDB: an integrative plant transcription factor database.
- Authors
Riaño-Pachón, Diego Mauricio; Ruzicic, Slobodan; Dreyer, Ingo; Mueller-Roeber, Bernd
- Abstract
Transcription factors (TFs) are key regulatory proteins that enhance or repress the transcriptional rate of their target genes by binding to specific promoter regions (i.e. cis-acting elements) upon activation or de-activation of upstream signaling cascades. TFs thus constitute master control elements of dynamic transcriptional networks. TFs have fundamental roles in almost all biological processes (development, growth and response to environmental factors) and it is assumed that they play immensely important functions in the evolution of species. In plants, TFs have been employed to manipulate various types of metabolic, developmental and stress response pathways. Cross-species comparison and identification of regulatory modules and hence TFs is thought to become increasingly important for the rational design of new plant biomass. Up to now, however, no computational repository is available that provides access to the largely complete sets of transcription factors of sequenced plant genomes.
- Publication
BMC bioinformatics, 2007, Vol 8, p42
- ISSN
1471-2105
- Publication type
Journal Article
- DOI
10.1186/1471-2105-8-42