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- Title
CoryneRegNet 4.0 - A reference database for corynebacterial gene regulatory networks.
- Authors
Baumbach, Jan
- Abstract
Detailed information on DNA-binding transcription factors (the key players in the regulation of gene expression) and on transcriptional regulatory interactions of microorganisms deduced from literature-derived knowledge, computer predictions and global DNA microarray hybridization experiments, has opened the way for the genome-wide analysis of transcriptional regulatory networks. The large-scale reconstruction of these networks allows the in silico analysis of cell behavior in response to changing environmental conditions. We previously published CoryneRegNet, an ontology-based data warehouse of corynebacterial transcription factors and regulatory networks. Initially, it was designed to provide methods for the analysis and visualization of the gene regulatory network of Corynebacterium glutamicum.
- Publication
BMC bioinformatics, 2007, Vol 8, p429
- ISSN
1471-2105
- Publication type
Journal Article
- DOI
10.1186/1471-2105-8-429