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- Title
Efficacy of different protein descriptors in predicting protein functional families.
- Authors
Ong, Serene A K; Lin, Hong Huang; Chen, Yu Zong; Li, Ze Rong; Cao, Zhiwei
- Abstract
Sequence-derived structural and physicochemical descriptors have frequently been used in machine learning prediction of protein functional families, thus there is a need to comparatively evaluate the effectiveness of these descriptor-sets by using the same method and parameter optimization algorithm, and to examine whether the combined use of these descriptor-sets help to improve predictive performance. Six individual descriptor-sets and four combination-sets were evaluated in support vector machines (SVM) prediction of six protein functional families.
- Publication
BMC bioinformatics, 2007, Vol 8, p300
- ISSN
1471-2105
- Publication type
Journal Article
- DOI
10.1186/1471-2105-8-300