We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality.
- Authors
Hart, G Traver; Lee, Insuk; Marcotte, Edward R
- Abstract
Identifying all protein complexes in an organism is a major goal of systems biology. In the past 18 months, the results of two genome-scale tandem affinity purification-mass spectrometry (TAP-MS) assays in yeast have been published, along with corresponding complex maps. For most complexes, the published data sets were surprisingly uncorrelated. It is therefore useful to consider the raw data from each study and generate an accurate complex map from a high-confidence data set that integrates the results of these and earlier assays.
- Publication
BMC bioinformatics, 2007, Vol 8, p236
- ISSN
1471-2105
- Publication type
Journal Article
- DOI
10.1186/1471-2105-8-236