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Title
Computational reconstruction of transcriptional regulatory modules of the yeast cell cycle.
Authors
Wu, Wei-Sheng; Li, Wen-Hsiung; Chen, Bor-Sen
Abstract
A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a living cell can coordinate the activities of many genes and carry out complex functions. Therefore, identifying TRMs is helpful for understanding gene regulation.