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- Title
Cross-platform comparability of microarray technology: intra-platform consistency and appropriate data analysis procedures are essential.
- Authors
Shi, Leming; Tong, Weida; Fang, Hong; Scherf, Uwe; Han, Jing; Puri, Raj K; Frueh, Felix W; Goodsaid, Federico M; Guo, Lei; Su, Zhenqiang; Han, Tao; Fuscoe, James C; Xu, Z Alex; Patterson, Tucker A; Hong, Huixiao; Xie, Qian; Perkins, Roger G; Chen, James J; Casciano, Daniel A
- Abstract
The acceptance of microarray technology in regulatory decision-making is being challenged by the existence of various platforms and data analysis methods. A recent report (E. Marshall, Science, 306, 630-631, 2004), by extensively citing the study of Tan et al. (Nucleic Acids Res., 31, 5676-5684, 2003), portrays a disturbingly negative picture of the cross-platform comparability, and, hence, the reliability of microarray technology.
- Publication
BMC bioinformatics, 2005, Vol 6 Suppl 2, pS12
- ISSN
1471-2105
- Publication type
Journal Article
- DOI
10.1186/1471-2105-6-S2-S12