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- Title
Proteins with two SUMO-like domains in chromatin-associated complexes: the RENi (Rad60-Esc2-NIP45) family.
- Authors
Novatchkova, Maria; Bachmair, Andreas; Eisenhaber, Birgit; Eisenhaber, Frank
- Abstract
Post-translational modification by Small Ubiquitin-like Modifiers (SUMO) has been implicated in protein targeting, in the maintenance of genomic integrity and in transcriptional control. But the specific molecular effects of SUMO modification on many target proteins remain to be elucidated. Recent findings point at the importance of SUMO-mediated histone NAD-dependent deacetylase (HDAC) recruitment in transcriptional regulation.
- Publication
BMC bioinformatics, 2005, Vol 6, p22
- ISSN
1471-2105
- Publication type
Journal Article
- DOI
10.1186/1471-2105-6-22