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- Title
Automated hierarchical classification of protein domain subfamilies based on functionally-divergent residue signatures.
- Authors
Neuwald, Andrew F; Lanczycki, Christopher J; Marchler-Bauer, Aron
- Abstract
The NCBI Conserved Domain Database (CDD) consists of a collection of multiple sequence alignments of protein domains that are at various stages of being manually curated into evolutionary hierarchies based on conserved and divergent sequence and structural features. These domain models are annotated to provide insights into the relationships between sequence, structure and function via web-based BLAST searches.
- Publication
BMC bioinformatics, 2012, Vol 13, p144
- ISSN
1471-2105
- Publication type
Journal Article
- DOI
10.1186/1471-2105-13-144