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- Title
Constructing a robust protein-protein interaction network by integrating multiple public databases.
- Authors
Martha, Venkata-Swamy; Liu, Zhichao; Guo, Li; Su, Zhenqiang; Ye, Yanbin; Fang, Hong; Ding, Don; Tong, Weida; Xu, Xiaowei
- Abstract
Protein-protein interactions (PPIs) are a critical component for many underlying biological processes. A PPI network can provide insight into the mechanisms of these processes, as well as the relationships among different proteins and toxicants that are potentially involved in the processes. There are many PPI databases publicly available, each with a specific focus. The challenge is how to effectively combine their contents to generate a robust and biologically relevant PPI network.
- Publication
BMC bioinformatics, 2011, Vol 12 Suppl 10, pS7
- ISSN
1471-2105
- Publication type
Journal Article
- DOI
10.1186/1471-2105-12-S10-S7