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- Title
Tiling array data analysis: a multiscale approach using wavelets.
- Authors
Karpikov, Alexander; Rozowsky, Joel; Gerstein, Mark
- Abstract
Tiling array data is hard to interpret due to noise. The wavelet transformation is a widely used technique in signal processing for elucidating the true signal from noisy data. Consequently, we attempted to denoise representative tiling array datasets for ChIP-chip experiments using wavelets. In doing this, we used specific wavelet basis functions, Coiflets, since their triangular shape closely resembles the expected profiles of true ChIP-chip peaks.
- Publication
BMC bioinformatics, 2011, Vol 12, p57
- ISSN
1471-2105
- Publication type
Journal Article
- DOI
10.1186/1471-2105-12-57