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- Title
A variational Bayes algorithm for fast and accurate multiple locus genome-wide association analysis.
- Authors
Logsdon, Benjamin A; Hoffman, Gabriel E; Mezey, Jason G
- Abstract
The success achieved by genome-wide association (GWA) studies in the identification of candidate loci for complex diseases has been accompanied by an inability to explain the bulk of heritability. Here, we describe the algorithm V-Bay, a variational Bayes algorithm for multiple locus GWA analysis, which is designed to identify weaker associations that may contribute to this missing heritability.
- Publication
BMC bioinformatics, 2010, Vol 11, p58
- ISSN
1471-2105
- Publication type
Journal Article
- DOI
10.1186/1471-2105-11-58