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- Title
Sequence-based identification of interface residues by an integrative profile combining hydrophobic and evolutionary information.
- Authors
Chen, Peng; Li, Jinyan
- Abstract
Protein-protein interactions play essential roles in protein function determination and drug design. Numerous methods have been proposed to recognize their interaction sites, however, only a small proportion of protein complexes have been successfully resolved due to the high cost. Therefore, it is important to improve the performance for predicting protein interaction sites based on primary sequence alone.
- Publication
BMC bioinformatics, 2010, Vol 11, p402
- ISSN
1471-2105
- Publication type
Journal Article
- DOI
10.1186/1471-2105-11-402