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- Title
ChIPpeakAnno: a Bioconductor package to annotate ChIP-seq and ChIP-chip data.
- Authors
Zhu, Lihua J; Gazin, Claude; Lawson, Nathan D; Pagès, Hervé; Lin, Simon M; Lapointe, David S; Green, Michael R
- Abstract
Chromatin immunoprecipitation (ChIP) followed by high-throughput sequencing (ChIP-seq) or ChIP followed by genome tiling array analysis (ChIP-chip) have become standard technologies for genome-wide identification of DNA-binding protein target sites. A number of algorithms have been developed in parallel that allow identification of binding sites from ChIP-seq or ChIP-chip datasets and subsequent visualization in the University of California Santa Cruz (UCSC) Genome Browser as custom annotation tracks. However, summarizing these tracks can be a daunting task, particularly if there are a large number of binding sites or the binding sites are distributed widely across the genome.
- Publication
BMC bioinformatics, 2010, Vol 11, p237
- ISSN
1471-2105
- Publication type
Journal Article
- DOI
10.1186/1471-2105-11-237