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- Title
Odefy--from discrete to continuous models.
- Authors
Krumsiek, Jan; Pölsterl, Sebastian; Wittmann, Dominik M; Theis, Fabian J
- Abstract
Phenomenological information about regulatory interactions is frequently available and can be readily converted to Boolean models. Fully quantitative models, on the other hand, provide detailed insights into the precise dynamics of the underlying system. In order to connect discrete and continuous modeling approaches, methods for the conversion of Boolean systems into systems of ordinary differential equations have been developed recently. As biological interaction networks have steadily grown in size and complexity, a fully automated framework for the conversion process is desirable.
- Publication
BMC bioinformatics, 2010, Vol 11, p233
- ISSN
1471-2105
- Publication type
Journal Article
- DOI
10.1186/1471-2105-11-233