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- Title
NLStradamus: a simple Hidden Markov Model for nuclear localization signal prediction.
- Authors
Nguyen Ba, Alex N; Pogoutse, Anastassia; Provart, Nicholas; Moses, Alan M
- Abstract
Nuclear localization signals (NLSs) are stretches of residues within a protein that are important for the regulated nuclear import of the protein. Of the many import pathways that exist in yeast, the best characterized is termed the 'classical' NLS pathway. The classical NLS contains specific patterns of basic residues and computational methods have been designed to predict the location of these motifs on proteins. The consensus sequences, or patterns, for the other import pathways are less well-understood.
- Publication
BMC bioinformatics, 2009, Vol 10, p202
- ISSN
1471-2105
- Publication type
Journal Article
- DOI
10.1186/1471-2105-10-202