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- Title
Metabolic flux balance analysis and the in silico analysis of Escherichia coli K-12 gene deletions.
- Authors
Edwards, J S; Palsson, B O
- Abstract
Genome sequencing and bioinformatics are producing detailed lists of the molecular components contained in many prokaryotic organisms. From this 'parts catalogue' of a microbial cell, in silico representations of integrated metabolic functions can be constructed and analyzed using flux balance analysis (FBA). FBA is particularly well-suited to study metabolic networks based on genomic, biochemical, and strain specific information.
- Publication
BMC bioinformatics, 2000, Vol 1, p1
- ISSN
1471-2105
- Publication type
Journal Article
- DOI
10.1186/1471-2105-1-1