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- Title
Glutathione-S-transferases in lung and sputum specimens, effects of smoking and COPD severity.
- Authors
Harju, Terttu; Mazur, Witold; Merikallio, Heta; Soini, Ylermi; Kinnula, Vuokko L
- Abstract
Oxidative stress plays a potential role in the pathogenesis and progression of chronic obstructive pulmonary disease (COPD). Glutathione S-transferases (GSTs) detoxify toxic compounds in tobacco smoke via glutathione-dependent mechanisms. Little is known about the regulation and expression of GSTs in COPD lung and their presence in airway secretions.
- Publication
Respiratory research, 2008, Vol 9, p80
- ISSN
1465-993X
- Publication type
Journal Article
- DOI
10.1186/1465-9921-9-80