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Title
IL13 gene polymorphisms modify the effect of exposure to tobacco smoke on persistent wheeze and asthma in childhood, a longitudinal study.
Authors
Sadeghnejad, Alireza; Karmaus, Wilfried; Arshad, S Hasan; Kurukulaaratchy, Ramesh; Huebner, Marianne; Ewart, Susan
Abstract
Tobacco smoke and genetic susceptibility are risk factors for asthma and wheezing. The aim of this study was to investigate whether there is a combined effect of interleukin-13 gene (IL13) polymorphisms and tobacco smoke on persistent childhood wheezing and asthma.