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- Title
Neonatal immune responses to TLR2 stimulation: influence of maternal atopy on Foxp3 and IL-10 expression.
- Authors
Schaub, Bianca; Campo, Monica; He, Hongzhen; Perkins, David; Gillman, Matthew W; Gold, Diane R; Weiss, Scott; Lieberman, Ellice; Finn, Patricia W
- Abstract
Maternal atopic background and stimulation of the adaptive immune system with allergen interact in the development of allergic disease. Stimulation of the innate immune system through microbial exposure, such as activation of the innate Toll-like-receptor 2 (TLR2), may reduce the development of allergy in childhood. However, little is known about the immunological effects of microbial stimulation on early immune responses and in association with maternal atopy.
- Publication
Respiratory research, 2006, Vol 7, p40
- ISSN
1465-993X
- Publication type
Journal Article
- DOI
10.1186/1465-9921-7-40