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- Title
Toll-like receptors in cellular subsets of human tonsil T cells: altered expression during recurrent tonsillitis.
- Authors
Mansson, Anne; Adner, Mikael; Cardell, Lars Olaf
- Abstract
The palatine tonsils have a pivotal role in immunological detection of airborne and ingested antigens like bacteria and viruses. They have recently been demonstrated to express Toll-like receptors (TLRs), known to recognize molecular structures on such microbes and activate innate immune responses. Their activation might also provide a link between innate and adaptive immunity. In the present study, the expression profile of TLR1-TLR10 was characterized in human tonsil T cells, focusing on differences between subsets of CD4+ T helper (Th) cells and CD8+ cytotoxic T lymphocytes (CTL). The study was also designed to compare the TLR expression in T cells from patients with recurrent tonsillitis and tonsillar hyperplasia.
- Publication
Respiratory research, 2006, Vol 7, p36
- ISSN
1465-993X
- Publication type
Journal Article
- DOI
10.1186/1465-9921-7-36