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- Title
Increased plasma mannose binding lectin levels are associated with bronchiolitis obliterans after lung transplantation.
- Authors
Budd, Steven J; Aris, Robert M; Medaiyese, Ayorinde A; Tilley, Stephen L; Neuringer, Isabel P
- Abstract
Long-term lung allograft survival is limited by bronchiolitis obliterans syndrome (BOS). Mannose binding lectin (MBL) belongs to the innate immune system, participates in complement activation, and may predispose to graft rejection. We investigated mannose binding (MBL) during cold ischemia and in tissue samples from explanted lungs with BOS, and assessed MBL and complement proteins in plasma post-lung transplantation relative to BOS staging.
- Publication
Respiratory research, 2012, Vol 13, p56
- ISSN
1465-993X
- Publication type
Journal Article
- DOI
10.1186/1465-9921-13-56