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- Title
Isolation and characterization of microparticles in sputum from cystic fibrosis patients.
- Authors
Porro, Chiara; Lepore, Silvia; Trotta, Teresa; Castellani, Stefano; Ratclif, Luigi; Battaglino, Anna; Di Gioia, Sante; Martínez, Maria C; Conese, Massimo; Maffione, Angela B
- Abstract
Microparticles (MPs) are membrane vesicles released during cell activation and apoptosis. MPs have different biological effects depending on the cell from they originate. Cystic fibrosis (CF) lung disease is characterized by massive neutrophil granulocyte influx in the airways, their activation and eventually apoptosis. We investigated on the presence and phenotype of MPs in the sputum, a rich non-invasive source of inflammation biomarkers, of acute and stable CF adult patients.
- Publication
Respiratory research, 2010, Vol 11, p94
- ISSN
1465-993X
- Publication type
Journal Article
- DOI
10.1186/1465-9921-11-94