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- Title
Early-life viral infection and allergen exposure interact to induce an asthmatic phenotype in mice.
- Authors
Siegle, Jessica S; Hansbro, Nicole; Herbert, Cristan; Rosenberg, Helene F; Domachowske, Joseph B; Asquith, Kelly L; Foster, Paul S; Kumar, Rakesh K
- Abstract
Early-life respiratory viral infections, notably with respiratory syncytial virus (RSV), increase the risk of subsequent development of childhood asthma. The purpose of this study was to assess whether early-life infection with a species-specific model of RSV and subsequent allergen exposure predisposed to the development of features of asthma.
- Publication
Respiratory research, 2010, Vol 11, p14
- ISSN
1465-993X
- Publication type
Journal Article
- DOI
10.1186/1465-9921-11-14