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- Title
Mono-allelic retrotransposon insertion addresses epigenetic transcriptional repression in human genome.
- Abstract
The article presents a research which examines the DNA methylation and histone modification of the locus which occurred mono-allelic young Alu, AluYa5 insertions, and the direct effect of retrotransposon in controlling gene expression. According to the research, the presence of mono-allelic Alu insertion cell line shows that the inactivation of neighboring gene expression is caused by polymorphic inserted repetitive elements.
- Publication
Journal of Biomedical Science, 2012, Vol 19, Issue 1, p13
- ISSN
1021-7770
- Publication type
Academic Journal
- DOI
10.1186/1423-0127-19-13