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- Title
Newcastle diseases virus strain V4UPM displayed oncolytic ability against experimental human malignant glioma.
- Authors
Zulkifli, M M; Ibrahim, R; Ali, A M; Aini, I; Jaafar, H; Hilda, S S; Alitheen, N B; Abdullah, J M
- Abstract
Newcastle disease virus (NDV) is a virus of paramyxovirus family and lately has been studied for the treatment of cancer in human. In this study, we successfully determined the oncolysis potential of NDV vaccine, V4UPM tested on the human glioblastoma multiform cell line (DBTRG.05MG) and human glioblastoma astrocytoma cell line (U-87MG) in vitro and in vivo. The V4UPM strain is a modified V4 strain developed as thermostable feed pellet vaccine for poultry.
- Publication
Neurological research, 2009, Vol 31, Issue 1, p3
- ISSN
0161-6412
- Publication type
Journal Article
- DOI
10.1179/174313208X325218