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- Title
The effect of polyphenolic extract from pine bark, Pycnogenol on the level of glutathione in children suffering from attention deficit hyperactivity disorder (ADHD).
- Authors
Dvoráková, Monika; Sivonová, Monika; Trebatická, Jana; Skodácek, Igor; Waczuliková, Iveta; Muchová, Jana; Duracková, Zdenka
- Abstract
Attention deficit hyperactivity disorder (ADHD) belongs to the neurodevelopmental disorders characterized by impulsivity, distractibility and hyperactivity. In the pathogenesis of ADHD genetic and non-genetic factors play an important role. It is assumed that one of non-genetic factors should be oxidative stress. Pycnogenol, an extract from the pine bark, consists of bioflavonoids, catechins, procyanidins and phenolic acids. Pycnogenol acts as powerful antioxidant, chelating agent; it stimulates the activities of some enzymes, like SOD, eNOS, and exhibits other biological activities.
- Publication
Redox report : communications in free radical research, 2006, Vol 11, Issue 4, p163
- ISSN
1743-2928
- Publication type
Journal Article
- DOI
10.1179/135100006X116664