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Title
Down-regulation of Stat3 induces apoptosis of human glioma cell: a potential method to treat brain cancer.
Authors
Ren, Wenwen; Duan, Yanhong; Yang, Yang; Ji, Yonghua; Chen, Fuxue
Abstract
Glioma is the most common brain tumor in central nervous system. Traditional therapies are not effective to cure this disease. Stat3 is a member of the signal transducer and activator of transcription family, and it has the potential to mediate cell survival, growth and differentiation.