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- Title
The effectiveness of sealants in managing caries lesions.
- Authors
Griffin, S O; Oong, E; Kohn, W; Vidakovic, B; Gooch, B F; Bader, J; Clarkson, J; Fontana, M R; Meyer, D M; Rozier, R G; Weintraub, J A; Zero, D T; CDC Dental Sealant Systematic Review Work Group
- Abstract
A barrier to providing sealants is concern about inadvertently sealing over caries. This meta-analysis examined the effectiveness of sealants in preventing caries progression. We searched electronic databases for comparative studies examining caries progression in sealed permanent teeth. We used a random-effects model to estimate percentage reduction in the probability of caries progression in sealed vs. unsealed carious teeth. Six studies, including 4 randomized-controlled trials (RCT) judged to be of fair quality, were included in the analysis (384 persons, 840 teeth, and 1090 surfaces). The median annual percentage of non-cavitated lesions progressing was 2.6% for sealed and 12.6% for unsealed carious teeth. The summary prevented fraction for RCT was 71.3% (95%CI: 52.8%-82.5, no heterogeneity) up to 5 years after placement. Despite variation among studies in design and conduct, sensitivity analysis found the effect to be consistent in size and direction. Sealing non-cavitated caries in permanent teeth is effective in reducing caries progression.
- Publication
Journal of dental research, 2008, Vol 87, Issue 2, p169
- ISSN
0022-0345
- Publication type
Journal Article
- DOI
10.1177/154405910808700211