Works matching DE "DRUG development"

Results: 5000

A Comprehensive Review on the Role of Natural Plants in Anti-Bacterial Activity.

Published in:

Journal of Drug Delivery & Therapeutics, 2025, v. 15, n. 7, p. 116, doi. 10.22270/jddt.v15i7.7200

By:

Tatiya, Anilkumar. U.;
Anil, Pagar Pranali

Publication type:

Article

Machine learning analysis of ARVC informed by sodium channel protein-based interactome networks.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1611342

By:

Zhu, Yanan;
Zhang, Hui;
Zhao, Xuan;
Wang, Xin;
Xing, Lina;
Yao, Sijie;
Jin, Xiao;
Li, Tingting;
Dai, Ting;
Ding, Xinyue;
Qi, Zhen;
Liu, Zongjun

Publication type:

Article

Cross-cultural treatment preferences: a call for diversity in drug development.

Published in:

Current Medical Research & Opinion, 2025, v. 41, n. 6, p. 1047, doi. 10.1080/03007995.2025.2537298

By:

Dijkgraaf, Dana M.;
Kiani, Pantea;
Zijlstra, Maureen N.;
Verster, Joris C.

Publication type:

Article

Exploring Aspergillus ochraceopetaliformis: Biosynthesis, chemical diversity, and pharmacological potential of its secondary metabolites.

Published in:

Journal of Applied Pharmaceutical Science, 2025, v. 15, n. 7, p. 67, doi. 10.7324/JAPS.2025.232603

By:

Mohamed, Hagar M.;
Mohamed, Shaimaa G. A.;
Ashour, Ahmed;
Hussein, Hazem G. A.;
Osman, Wadah;
Mohamed, Gamal A.;
Ibrahim, Sabrin R. M.

Publication type:

Article

Design, synthesis, and biological evaluation of potent anti-fatigue compounds based on 1-BCP targeting the AMPA receptor.

Published in:

Arabian Journal of Chemistry, 2025, v. 18, n. 5, p. 1, doi. 10.25259/AJC_89_2025

By:

Yang, Xin;
Cui, Yaowen;
He, Zhaolun;
Xu, Jing;
Chen, Tingting;
Liu, Shuchen;
Wang, Lin;
Zhang, Shouguo

Publication type:

Article

Sustainable synthesis of bivalent Ni2+, Co2+, and Cu2+ Schiff base complexes via ball milling as a green approach: A study of spectroscopic characterization, cyclic voltammetry, bioactivity, DFT analysis, SAR, drug likeness, and molecular docking

Published in:

Arabian Journal of Chemistry, 2025, v. 18, n. 4, p. 1, doi. 10.25259/AJC_56_2025

By:

Abou-Melha, Khlood Saad A.

Publication type:

Article

Incremental therapeutic value of FDA-designated "breakthrough" drugs based on ratings from four international organizations: a cross-sectional study Open Access.

Published in:

Journal of Pharmaceutical Health Services Research, 2025, v. 16, n. 2, p. 1, doi. 10.1093/jphsr/rmaf009

By:

Borisova, Elizaveta;
Darrow, Jonathan;
Lexchin, Joel

Publication type:

Article

Moving the needle on immune checkpoint inhibitors with novel targets: are we being TIMid or LAGging behind?

Published in:

Oncologist, 2025, v. 30, n. 7, p. 1, doi. 10.1093/oncolo/oyaf145

By:

Park, Changsu Lawrence;
Bedard, Philippe L

Publication type:

Article

3D conformation and crystal interaction insights into drug development challenges for HCV drug analogues via molecular simulations.

Published in:

Communications Chemistry, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42004-025-01618-8

By:

Hong, Richard S.;
Mattei, Alessandra;
Tuckerman, Mark E.;
Sheikh, Ahmad Y.

Publication type:

Article

A Conversation With Amy Racine‐Poon.

Published in:

International Statistical Review, 2025, v. 93, n. 2, p. 183, doi. 10.1111/insr.12605

By:

Sverdlov, Oleksandr

Publication type:

Article

Strychnos peckii B.L. Rob.: secondary metabolite annotation by liquid chromatography tandem high-resolution mass spectrometry with insights from biogenesis.

Published in:

Analytical & Bioanalytical Chemistry, 2025, v. 417, n. 20, p. 4557, doi. 10.1007/s00216-025-05967-0

By:

Cassas, Fernando;
Santos, Carla L. G.;
da Silva, Felipe M. A.;
Cass, Quezia B.

Publication type:

Article

The Hsp90β Isoform: An Attractive Target for Drug Development.

Published in:

Medicinal Research Reviews, 2025, v. 45, n. 5, p. 1452, doi. 10.1002/med.22114

By:

Chaudhury, Subhabrata;
D'Amico, Terin;
Blagg, Brian S. J.

Publication type:

Article

大蒜活性成分抗肿瘤作用及其机制研究进展.

Published in:

Journal of Food Safety & Quality, 2025, v. 16, n. 16, p. 166, doi. 10.19812/j.cnki.jfsq11-5956/ts.20250327001

By:

胡艳茹;
邓晓东;
赵志伟;
刘祎雯;
杨雯静;
盛宇涵;
李伟;
舒馨;
张薇薇

Publication type:

Article

Recaticimab: First Approval.

Published in:

Drugs, 2025, v. 85, n. 8, p. 1067, doi. 10.1007/s40265-025-02199-5

By:

Lamb, Yvette N.

Publication type:

Article

Sipavibart: First Approval.

Published in:

Drugs, 2025, v. 85, n. 8, p. 1049, doi. 10.1007/s40265-025-02186-w

By:

Keam, Susan J.

Publication type:

Article

Limertinib: First Approval.

Published in:

Drugs, 2025, v. 85, n. 8, p. 1055, doi. 10.1007/s40265-025-02184-y

By:

Lee, Arnold

Publication type:

Article

Accelerating the Understanding of Biosensors Through the Lens of Cells: State of the Field, Emerging Directions, Advances, and Challenges.

Published in:

Applied Biochemistry & Biotechnology, 2025, v. 197, n. 7, p. 4224, doi. 10.1007/s12010-025-05209-0

By:

Narang, Jasjeet;
Rana, Niket;
Chauhan, Arjun;
Kumari, Anushka;
Minhas, Vanshika

Publication type:

Article

Efficient and Rapid Arylation of NH₂‐Unprotected Bromobisindole Ethanamines via Suzuki‐Miyaura Coupling: Generating New Leads Against Leishmania.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 43, p. 1, doi. 10.1002/chem.202500637

By:

Buono, Alessandro;
Diotallevi, Aurora;
Maestrini, Sara;
Verboni, Michele;
Kiuru, Paula;
Galluzzi, Luca;
Duranti, Andrea;
Olivieri, Diego;
Lucarini, Simone

Publication type:

Article

Advances and challenges of targeting epicardial adipose tissue (EAT) and perivascular adipose tissue (PVAT).

Published in:

Cardiovascular Diabetology, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12933-025-02763-z

By:

Liu, Dan;
Chen, Wujun;
Guo, Zhu;
Gao, Qun;
Wang, Bin;
Wang, Jie;
Hu, Weichao;
Wang, Chao;
Wang, Shuai;
Wu, Xiaolin;
Xu, Mantao;
Lan, Ganqiu

Publication type:

Article

Genomic characterization and pre-clinical evaluation of a new polyvalent lytic Loughborough phage.

Published in:

Applied Microbiology & Biotechnology, 2025, v. 109, n. 1, p. 1, doi. 10.1007/s00253-025-13559-2

By:

Sherif, Mahmoud M.;
Abdelaziz, Neveen A.;
Saleh, Sarra E.;
Aboshanab, Khaled M.

Publication type:

Article

In silico target identification and pharmacokinetic profiling of 2-aryl-quinoline-4-carboxylic acid derivatives as potential antileishmanial agents.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1621059

By:

da Silva, Marília Cecília;
Viana, Jéssika de Oliveira;
Olegário, Tayná Rodrigues;
Sabino, Jayne Maria;
Barbosa, Euzébio Guimarães;
Chaves, Elton José Ferreira;
Rocha, Gerd Bruno;
Lima-Junior, Claudio Gabriel;
Weber, Karen Cacilda

Publication type:

Article

Preclinical evaluation of dose-dependent effects of photobiomodulation therapy on persistent inflammation in the temporomandibular joint.

Published in:

Journal of Oral & Facial Pain & Headache, 2025, v. 39, n. 2, p. 183, doi. 10.22514/jofph.2025.037

By:

Carvalho, Vinicius Almeida;
Martins, Amanda Almeida;
de Carvalho Desiderá, Amanda;
Nascimento, Glauce Crivelaro;
Magri, Laís Valencise;
Leite-Panissi, Christie Ramos Andrade

Publication type:

Article

Dose-response characterization: A key to success in drug development.

Published in:

Clinical Trials, 2025, v. 22, n. 4, p. 384, doi. 10.1177/17407745251350289

By:

Bretz, Frank;
Bornkamp, Björn;
Dumortier, Thomas

Publication type:

Article

Comparison of adaptive seamless Phase 2/3 designs for dose selection in clinical trials with multiple endpoints.

Published in:

Clinical Trials, 2025, v. 22, n. 4, p. 405, doi. 10.1177/17407745251338592

By:

Jin, Man

Publication type:

Article

Military influences on the evolution of clinical trials throughout history.

Published in:

Clinical Trials, 2025, v. 22, n. 4, p. 501, doi. 10.1177/17407745241309054

By:

Malshy, Kamil;
Steinmetz, Alexis;
Yuen, Kit;
Bandari, Jathin;
Rabinowitz, Ronald

Publication type:

Article

Cryo-EM reveals an extrahelical allosteric binding site at the M5 mAChR.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-62212-z

By:

Burger, Wessel A. C.;
Mobbs, Jesse I.;
Rana, Bhavika;
Wang, Jinan;
Joshi, Keya;
Gentry, Patrick R.;
Yeasmin, Mahmuda;
Venugopal, Hariprasad;
Bender, Aaron M.;
Lindsley, Craig W.;
Miao, Yinglong;
Christopoulos, Arthur;
Valant, Celine;
Thal, David M.

Publication type:

Article

New opportunities and current challenges using animal models for the discovery of novel countermeasures for acute radiation syndrome.

Published in:

Expert Opinion on Drug Discovery, 2025, v. 20, n. 8, p. 1045, doi. 10.1080/17460441.2025.2528966

By:

Singh, Vijay K.;
Seed, Thomas M.

Publication type:

Article

Synthesis, molecular modeling and harnessing the antimicrobial activity of new pyrazine-thiadiazole hybrids.

Published in:

BMC Chemistry, 2025, v. 19, n. 1, p. 1, doi. 10.1186/s13065-025-01587-y

By:

Abumelha, Hana M.;
Halawani, Nuha M.;
Alharbi, Abdulrahman S.;
Alsulami, Rabah N.;
Qurban, Jihan;
Alomari, Khadra B.;
Al-Bonayan, Ameena M.;
El-Metwaly, Nashwa

Publication type:

Article

Structure-based virtual screening, molecular docking, and MD simulation studies: An in-silico approach for identifying potential MBL inhibitors.

Published in:

PLoS ONE, 2025, v. 20, n. 7, p. 1, doi. 10.1371/journal.pone.0324836

By:

Noumi, Emira;
Snoussi, Mejdi;
Bouali, Nouha;
Alshammari, Mamdouh M.;
Altayb, Hisham N.;
Afzal, Muhammad;
De Feo, Vincenzo

Publication type:

Article

Obesity: A Persistent Puzzle-Unveiling Past Missteps and Future Promise in Drug Discovery.

Published in:

Karbala Journal of Pharmaceutical Sciences, 2024, v. 15, n. 25, p. 149, doi. 10.62472/kjps.v15.i25.149-174

By:

AlKhafaji, Sura L.;
Al-Owaidi, Mohammed Fanokh

Publication type:

Article

Hybrids of 4-aminoquinolines and adamantane as inhibitors of AChE.

Published in:

Journal of the Serbian Chemical Society, 2025, v. 90, n. 5, p. 545, doi. 10.2298/JSC250131014K

By:

KOMATOVIĆ, KATARINA;
MATOŠEVIĆ, ANA;
ZLATOVIĆ, MARIO;
SLADIĆ, DUŠAN;
BOSAK, ANITA;
OPSENICA, DEJAN M.

Publication type:

Article

Optimal Design of Drug–Drug Interaction Studies for the GLP‐1 Receptor Agonist Drug Class for Weight Management: Closing a Potential Data Gap.

Published in:

Journal of Clinical Pharmacology, 2025, v. 65, n. 8, p. 1056, doi. 10.1002/jcph.70020

By:

Weber, Elijah;
Trivedi, Ashit;
Barbour, April M.

Publication type:

Article

Dose Ranging in Pediatric Drug Development Trials Submitted to the US FDA 2012–2020.

Published in:

Journal of Clinical Pharmacology, 2025, v. 65, n. 8, p. 955, doi. 10.1002/jcph.70016

By:

Lee, Carlton K. K.;
Kwon, Eugenia;
Green, Francis G.;
Kelley, Connor M. I.;
Pham, Jennifer;
Abulwerdi, Gelareh;
Samuels, Sherbet;
Green, Dionna J.;
Burckart, Gilbert J.

Publication type:

Article

A Physiologically Based Pharmacokinetic Model of an Oral Tyrosine Kinase 2 Inhibitor Deucravacitinib in Healthy Adults.

Published in:

Journal of Clinical Pharmacology, 2025, v. 65, n. 8, p. 1011, doi. 10.1002/jcph.70014

By:

Chen, Xinyue;
Lin, Zhoumeng

Publication type:

Article

The 2015 Nobel Prize Laureates in Physiology or Medicine.

Published in:

Vojnosanitetski Pregled: Military Medical & Pharmaceutical Journal of Serbia, 2015, v. 72, n. 11, p. 951, doi. 10.2298/VSP1511951M

By:

Mikić, Dragan

Publication type:

Article

The first pharmacy in Vranje with the educated pharmacist and its development.

Published in:

Vojnosanitetski Pregled: Military Medical & Pharmaceutical Journal of Serbia, 2014, v. 71, n. 10, p. 978, doi. 10.2298/VSP130819048K

By:

Krajnović, Dušanka M.;
Arsić, Jasmina B.;
Milošević Georgijev, Andrijana M.;
Manojlović, Jelena M.

Publication type:

Article

Patent law protection of inventions in medicine and pharmaceutical industry.

Published in:

Vojnosanitetski Pregled: Military Medical & Pharmaceutical Journal of Serbia, 2013, v. 70, n. 6, p. 600, doi. 10.2298/VSP1306600M

By:

Miladinović, Zoran;
Varga, Siniša;
Radojković, Marija

Publication type:

Article

Phenotyping Before Starting Treatment in COPD?

Published in:

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2017, v. 14, n. 3, p. 367, doi. 10.1080/15412555.2017.1303041

By:

Siafakas, Nikolaos;
Corlateanu, Alexandru;
Fouka, Evangelia

Publication type:

Article

The COPD Pipeline XXIV.

Published in:

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2013, v. 10, n. 5, p. 625, doi. 10.3109/15412555.2013.832093

By:

Gross, Nicholas J.

Publication type:

Article

The COPD Pipeline XXIII.

Published in:

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2013, v. 10, n. 4, p. 545, doi. 10.3109/15412555.2013.811988

By:

Gross, Nicholas

Publication type:

Article

The COPD Biomarker Qualification Consortium (CBQC).

Published in:

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2013, v. 10, n. 3, p. 367, doi. 10.3109/15412555.2012.752807

By:

Casaburi, Richard;
Celli, Bartolome;
Crapo, James;
Criner, Gerard;
Croxton, Thomas;
Gaw, Alasdair;
Jones, Paul;
Kline-Leidy, Nancy;
Lomas, David A.;
Merrill, Debora;
Polkey, Michael;
Rennard, Stephen;
Sciurba, Frank;
Tal-Singer, Ruth;
Stockley, Robert;
Turino, Gerry;
Vestbo, Jorgen;
Walsh, John

Publication type:

Article

Patient-reported Outcome (PRO) Measures for Clinical Trials of COPD: The EXACT and E-RS.

Published in:

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2013, v. 10, n. 3, p. 393, doi. 10.3109/15412555.2013.795423

By:

Leidy, Nancy K.;
Murray, Lindsey T.

Publication type:

Article

The COPD Pipeline XXI.

Published in:

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2013, v. 10, n. 2, p. 266, doi. 10.3109/15412555.2013.771023

By:

Gross, Nicholas

Publication type:

Article

The COPD Pipeline XX.

Published in:

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2013, v. 10, n. 1, p. 104, doi. 10.3109/15412555.2013.766103

By:

Gross, Nicholas

Publication type:

Article

The COPD Pipeline XVI.

Published in:

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2012, v. 9, n. 3, p. 310, doi. 10.3109/15412555.2012.683968

By:

Gross, Nicholas;
Mann, Marianne

Publication type:

Article

The COPD Pipeline XV.

Published in:

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2012, v. 9, n. 2, p. 203, doi. 10.3109/15412555.2012.665756

By:

Gross, Nicholas

Publication type:

Article

Knowledge-driven approaches for the guidance of first-in-children dosing.

Published in:

Pediatric Anesthesia, 2011, v. 21, n. 3, p. 206, doi. 10.1111/j.1460-9592.2010.03473.x

By:

Edginton, Andrea N.

Publication type:

Article

Role of modeling and simulation in pediatric investigation plans.

Published in:

Pediatric Anesthesia, 2011, v. 21, n. 3, p. 214, doi. 10.1111/j.1460-9592.2011.03523.x

By:

Manolis, Efthymios;
Osman, Tariq Eldirdiry;
Herold, Ralf;
Koenig, Franz;
Tomasi, Paolo;
Vamvakas, Spiros;
Raymond, Agnes Saint

Publication type:

Article

Emerging pharmacological agents for post-traumatic stress disorder show promise, but more evidence is needed.

Published in:

Drugs & Therapy Perspectives, 2024, v. 40, n. 12, p. 479, doi. 10.1007/s40267-024-01123-3

By:

Zhuang-Yan, Amy

Publication type:

Article

Sovateltide in cerebral ischaemic stroke: a profile of its use.

Published in:

Drugs & Therapy Perspectives, 2024, v. 40, n. 7, p. 250, doi. 10.1007/s40267-024-01094-5

By:

Fung, Simon;
Syed, Yahiya Y.

Publication type:

Article