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Title
Neuromyelitis optica: a demyelinating disease characterized by acute destruction and regeneration of perivascular astrocytes.
Authors
Parratt, John D E; Prineas, John W
Abstract
A serum antibody directed against astrocytes is present in a high proportion of patients with neuromyelitis optica (NMO). The pathogenicity of the antibody is uncertain because no consistent astrocyte lesion is known to occur in NMO.