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- Title
Spinal cord grey matter lesions in multiple sclerosis detected by post-mortem high field MR imaging.
- Authors
Gilmore, C P; Geurts, J J G; Evangelou, N; Bot, J C J; van Schijndel, R A; Pouwels, P J W; Barkhof, F; Bö, L
- Abstract
Post-mortem studies demonstrate extensive grey matter demyelination in MS, both in the brain and in the spinal cord. However the clinical significance of these plaques is unclear, largely because they are grossly underestimated by MR imaging at conventional field strengths. Indeed post-mortem MR studies suggest the great majority of lesions in the cerebral cortex go undetected, even when performed at high field. Similar studies have not been performed using post-mortem spinal cord material.
- Publication
Multiple sclerosis (Houndmills, Basingstoke, England), 2009, Vol 15, Issue 2, p180
- ISSN
1352-4585
- Publication type
Journal Article
- DOI
10.1177/1352458508096876