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- Title
The effect of monotherapy and combined therapy with NSC-631570 (ukrain) on growth of low- and high-metastasizing B16 melanoma in mice.
- Authors
Skivka, Lm; Susak, Yam; Trompak, Oo; Kudryavets, Yui; Bezdeneznikh, N; Semesiuk, N; Lykhova, O
- Abstract
NSC-631570 (ukrain) is a semisynthetic derivative of the Chelidonium majus alcaloids and the alkylans thiotepa. It exerts a selective cytotoxic effect on tumor cells in vitro and in vivo and shows the ability to modulate immunocyte functions. Purpose. The aim of our work was to carry out a comparative investigation of the effects of NSC-631570 alone or in combination with pathogen-associated molecules (PAM) on the growth of low- and high-metastasizing melanoma B16 in mice.
- Publication
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2011, Vol 17, Issue 4, p339
- ISSN
1477-092X
- Publication type
Journal Article
- DOI
10.1177/1078155210382470