We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Poorly differentiated carcinomas of the thyroid gland: a review of the clinicopathologic features of a series of 28 cases of a heterogeneous, clinically aggressive group of thyroid tumors.
- Authors
Sobrinho-Simões, Manuel; Sambade, Clara; Fonseca, Elsa; Soares, Paula
- Abstract
We evaluated the clinicopathologic, immunohistochemical, lectin histochemical, ultrastructural and morphometric characteristics of a series of 28 poorly differentiated carcinomas of the thyroid (PDCT). The 28 tumors were classified according to their predominant growth pattern as insular (n=12), trabecular (n=10) and solid subtypes (n=6). The overall mortality rate was 46%. No significant differences were found among the 3 subtypes. Data obtained by lectin histochemistry, electron microscopy, and morphometry point to a closer relationship of PDCT to follicular than to papillary carcinoma. Our results do not support the subdivision of PDCT into subtypes.
- Publication
International journal of surgical pathology, 2002, Vol 10, Issue 2, p123
- ISSN
1066-8969
- Publication type
Journal Article
- DOI
10.1177/106689690201000205