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- Title
A multicentre prospective controlled study to determine the safety of trazodone and nefazodone use during pregnancy.
- Authors
Einarson, Adrienne; Bonari, Lori; Voyer-Lavigne, Sharon; Addis, Antonio; Matsui, Doreen; Johnson, Yvette; Koren, Gideon
- Abstract
Trazodone and nefazodone are phenylpiperazine antidepressants. Currently, there are no adequate, well-controlled studies on the fetal safety of these drugs. Our primary objective was to determine whether the use of trazodone or nefazodone during pregnancy is associated with an increased risk for major malformations. Secondary outcomes of interest included rates of spontaneous and therapeutic abortions, rates of premature labour, and birth weight.
- Publication
Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2003, Vol 48, Issue 2, p106
- ISSN
0706-7437
- Publication type
Journal Article
- DOI
10.1177/070674370304800207