Title

Biofilm Formations in Nasopharyngeal Tissues of Patients with Nasopharyngeal Osteoradionecrosis.

Authors

Tsai, Yih-Jeng; Lin, Yu-Chi; Wu, Wen-Bin; Chiu, Po-Han; Lin, Brian J.; Hao, Sheng-Po

Abstract

The article presents a study on the presence of nasopharynx biofilms among patients with nasopharyngeal cancer (NPC), osteoradionecrosis (ORN), and patients with NPC but no ORN. It says that 27 NPC, 15 ORN, and 12 without ORN patients had receive radiotherapy and were evaluated by fluorescence microscopy to determine biofilms formation. It concludes that the presence of biofilms, which are common with NPC patients with ORN, contribute to the resistance of antibiotic treatment.

Subjects

BIOFILMS; NASOPHARYNX cancer patients; OSTEORADIONECROSIS; RADIOTHERAPY; FLUORESCENCE microscopy; ANTIBIOTIC prophylaxis; THERAPEUTICS

Publication

Otolaryngology-Head & Neck Surgery, 2013, Vol 148, Issue 4, p633

ISSN

0194-5998

Publication type

Academic Journal

DOI

10.1177/0194599812474971