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- Title
Hooked! Modeling human disease in zebrafish.
- Authors
Santoriello, Cristina; Zon, Leonard I
- Abstract
Zebrafish have been widely used as a model system for studying developmental processes, but in the last decade, they have also emerged as a valuable system for modeling human disease. The development and function of zebrafish organs are strikingly similar to those of humans, and the ease of creating mutant or transgenic fish has facilitated the generation of disease models. Here, we highlight the use of zebrafish for defining disease pathways and for discovering new therapies.
- Publication
The Journal of clinical investigation, 2012, Vol 122, Issue 7, p2337
- ISSN
1558-8238
- Publication type
Journal Article
- DOI
10.1172/JCI60434