We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Melanoma genetics and the development of rational therapeutics.
- Authors
Chudnovsky, Yakov; Khavari, Paul A; Adams, Amy E
- Abstract
Melanoma is a cancer of the neural crest-derived cells that provide pigmentation to skin and other tissues. Over the past 4 decades, the incidence of melanoma has increased more rapidly than that of any other malignancy in the United States. No current treatments substantially enhance patient survival once metastasis has occurred. This review focuses on recent insights into melanoma genetics and new therapeutic approaches being developed based on these advances.
- Publication
The Journal of clinical investigation, 2005, Vol 115, Issue 4, p813
- ISSN
0021-9738
- Publication type
Journal Article
- DOI
10.1172/JCI24808